S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate...

Details S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate... S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate...

C - Chemistry, Metallurgy

07

C

C07C 323/59 (2006.01) A61K 31/198 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2518737

A crystalline maleate salt of S-[2-[(l -Iminoethyl)aminojethyl]-2-methyl-L- cysteine is disclosed. The crystalline salt has absorption of less than one percent water by weight at 90% R.H. at 25 ~C, a melting point of 123 ~C, and aqueous solubility in excess of 230 mg ml-I.

L'invention se rapporte à un sel cristallin de maléate de S-[2-[(l-Iminoéthyl)amino]éthyl]-2-méthyl-L-cystéine présentant un taux d'absorption inférieur à un pour cent en poids d'eau à une humidité relative de 90 % et une température de 25 ·C, un point de fusion de 123 ·C, et une solubilité aqueuse supérieure à 230 mg ml?-1¿.

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