(s)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,...

Details (s)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,... (s)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,...

C - Chemistry, Metallurgy

07

D

167/231, 260/273

C07D 471/04 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2013136

The novel (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclo- propyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine- 3-carboxylic acid, lower alkyl esters and pharmaceutically acceptable salts thereof are described as well as a method for its manufacture, formulation, and use in treating bacterial infections.

L'invention porte sur de nouveaux esters alkyliques (alkyle inf.) d'acide (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclo-propyl-6-fluoro-1,4-dihydro-4-oxo-1,8- naphtyridine-3-carboxylique et leurs sels de qualité pharmaceutique, ainsi que sur leur préparation, leur formulation et leur emploi pour le traitement d'infections bactériennes.

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