S-allylmercaptoglutathione and uses thereof

Details S-allylmercaptoglutathione and uses thereof S-allylmercaptoglutathione and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 5/037 (2006.01) A61K 38/06 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2391969

S-Allylmercaptoglutathione of formula (I) is prepared by reaction of glutathione with allicin or with diallyl disulfide and can be used in pharmaceutical compositions for the treatment of atherosclerosis, coronary artery diseases, thrombosis, high levels of cholesterol and blood lipids, high blood pressure, control of weight, Alzheimer disease, glaucoma, cancer and inflammatory disorders.

Selon l'invention, du S-Allylmercaptoglutathione de formule (I) est préparé par réaction de glutathione avec de l'allicine ou du disulfure de diallyle, et peut être utilisé dans des compositions pharmaceutiques destinées au traitement d'athérosclérose, de coronaropathies, de thromboses, de taux élevés de cholestérol et de lipides sanguins, de pressions artérielles élevées, de la maladie d'Alzheimer, des glaucomes, du cancer, de troubles inflammatoires, et pour le contrôle du poids.

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