(s)- hydroxynitrile lyases with improved substrate...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/88 (2006.01) C12P 13/00 (2006.01) C12P 17/04 (2006.01)

Patent

CA 2277594

(S)-Hydroxynitrile lyases which have an improved substrate acceptance and which are derived from the Hevea brasiliensis and Manihot esculenta (S)-hydroxynitrile lyases, wherein one or more bulky amino acid residues within the hydrophobic channel leading to the active center have been replaced with less bulky amino acid residues.

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