(s)-n-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium...

C - Chemistry – Metallurgy – 07 – D

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C07D 489/08 (2006.01) A61K 31/485 (2006.01) A61P 1/12 (2006.01)

Patent

CA 2670303

Novel (S)-N-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs are disclosed. Pharmaceutical compositions containing the (S)-N-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs and methods for their pharmaceutical uses are also disclosed. Such analogs are disclosed as being useful in treating, among varying conditions, hypermotility of the gastrointestinal tract.

L'invention porte sur de nouveaux (S)-N-stéréoisomères d'analogues de 4,5-époxy-morphinanium saturés en 7,8. L'invention porte également sur des compositions pharmaceutiques contenant les (S)-N-stéréoisomères d'analogues de 4,5-époxy-morphinanium saturés en 7,8, et sur des procédés pour leurs utilisations pharmaceutiques. De tels analogues sont décrits comme étant utiles pour traiter, entre diverses conditions, l'hypermotilité du tractus gastro-intestinal.

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