S-substituted 11.beta.-benzaldoxime-estra-4,9-diene-carbonic...

Details S-substituted 11.beta.-benzaldoxime-estra-4,9-diene-carbonic... S-substituted 11.beta.-benzaldoxime-estra-4,9-diene-carbonic...

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) A61K 31/565 (2006.01) C07J 43/00 (2006.01)

Patent

CA 2322471

Thiol esters of S-substituted 11.beta.-benzaldoxime-estra-1,9-diene carboxylic acids of the general formula I (See formula I) and their pharmaceutically acceptable salts, a method for their synthesis and pharmaceutical preparations containing these compounds. The compounds arc bound to progesterone receptors and have a distinctly reduced anti-glucocorticoid action.

L'invention concerne des thiolesters d'acide 11 beta -benzaldoxim-estra-4,9-diène-carbonique de la formule générale (I), et leurs sels pharmaceutiquement acceptables. Elle concerne également leur procédé de production et des préparations pharmaceutiques contenant ces composés. Les composés sont liés au récepteur de la progestérone et possèdent un effet antiglucocorticoïde notablement réduit.

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