S-triazolo¬3,4-i|purine derivatives

Details S-triazolo¬3,4-i|purine derivatives S-triazolo¬3,4-i|purine derivatives

C - Chemistry, Metallurgy

07

D

167/220, 260/242

C07D 487/14 (2006.01) A61K 31/52 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2025413

- 79 - There are disclosed s-triazolo[3,4-i]purine derivatives represented by formula: (see fig. I) wherein Y-Z represents (see fig II) or (see fig. III) where R4 represents hydrogen, alkyl, substituted or unsubstituted aromatic heterocyclic group or substituted or unsubstituted aryl; and X2 represents oxygen, sulfur or NH; each of R1 and R2 independently represents hydrogen, alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; R3 represents alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; X1 represents oxygen or sulfur; and ~ represents a single bond or a double bond or pharmaceutically acceptable salts thereof.

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