S1p receptors modulators and their use thereof

Details S1p receptors modulators and their use thereof S1p receptors modulators and their use thereof

C - Chemistry, Metallurgy

07

D

C07D 413/10 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/343 (2006.01) A61K 31/382 (2006.01) A61K 31/397 (2006.01) A61K 31/403 (2006.01) A61K 31/41 (2006.01) A61K 31/4164 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 33/00 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) A61P 43/00 (2006.01) C07C 9/02 (2006.01) C07C 15/04 (2006.01) C07C 215/10 (2006.01) C07C 215/68 (2006.01) C07C 225/16 (2006.01)

Patent

CA 2740484

The invention relates to novel compounds that have S1P receptor modulating activity. Further, the invention relates to a pharmaceutical comprising at least one compound of the invention for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression, for example, autoimmune response. A further aspect of the invention relates to the use of a pharmaceutical comprising at least one compound of the invention for the manufacture of a medicament for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression such as autoimmune response.

Cette invention concerne de nouveaux composés présentant une activité modulatrice des récepteurs S1P. Linvention concerne également un agent pharmaceutique comprenant au moins un composé de linvention utilisé dans le traitement de maladies et/ou daffections causées par ou associées avec une activité modulatrice ou une expression des récepteurs S1P inappropriées, par exemple une réponse auto-immune. Linvention concerne par ailleurs lutilisation dun agent pharmaceutique comprenant au moins un composé de linvention dans la fabrication dun médicament destiné au traitement de maladies et/ou daffections causées par ou associées avec une activité modulatrice ou une expression des récepteurs S1P inappropriées telle quune réponse auto-immune.

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