Saccharide-containing protein conjugates and uses thereof

Details Saccharide-containing protein conjugates and uses thereof Saccharide-containing protein conjugates and uses thereof

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 43/00 (2006.01) C07H 15/08 (2006.01) C07H 15/26 (2006.01) C07K 14/59 (2006.01) C07K 17/02 (2006.01) C07K 17/10 (2006.01)

Patent

CA 2696699

Conjugates of a saccharide and a biomolecule, covalently linked therebetween via a non-hydrophobic linker and methods of preparing same are disclosed. Also disclosed are medical uses utilizing such conjugates. Glycosylation reagents for use in preparing these conjugates are also disclosed. Glycosylated proteins, characterized by improved performance, are also disclosed.

L'invention porte sur des conjugués d'un saccharide et d'une biomolécule, liés de façon covalente entre eux par un lieur non hydrophobe, et sur des procédés de préparation de ces conjugués. L'invention porte également sur des utilisations médicales faisant usage de tels conjugués. L'invention porte également sur des réactifs de glycosylation destinés à être utilisés dans la préparation de ces conjugués. L'invention porte également sur des protéines glycosylées caractérisées par une performance accrue.

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