C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 1/00 (2006.01) C07H 1/06 (2006.01) C07H 3/00 (2006.01)
Patent
CA 2458651
The invention relates to a process for the sulfation of saccharides, which process comprises: (a) obtaining a starting saccharide in sodium salt form, wherein the starting saccharide comprises a heterogenous or homogenous collection of monosaccharides, disaccharides, and oligosaccharides or mixtures thereof, more than 85% of which are composed maximally of eight sugar residues; (b) dissolving the starting saccharide sodium salt in a dipolar aprotic solvent selected from the group consisting of pyridine, pyridine-DMF, and pyridine-DMSO, thereby forming a starting saccharide salt- solvent mixture; and (c) treating the starting saccharide salt-solvent mixture with a sulfating agent to produce a sulfated saccharide.
La présente invention concerne des procédés de sulfatation de saccharides. L'invention concerne en particulier des procédés de sulfatation de saccharides de bas poids moléculaire dérivés de glycosaminoglycanes.
Ivax Research Inc.
Sim & Mcburney
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