Saccharin derivatives as orally active elastase inhibitors

Details Saccharin derivatives as orally active elastase inhibitors Saccharin derivatives as orally active elastase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/505 (2006.01) A61P 29/00 (2006.01) C07D 221/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2395486

Orally active compounds of general formula (I) wherein R1 is methyl, ethyl or 2-morpholino-ethyl group, R2 is piperidino, morpholino or 4-methyl-piperazinyl group, n is 2 or 3 and their salts, solvates and hydrates.

La présente invention concerne des composés oralement actifs, de formule générale (I), dans laquelle R?1¿ représente un groupe méthyle, éthyle ou 2-morpholino-éthyle, R?2¿ représente un groupe pipéridino, morpholino ou 4-méthyl-pipérazinyle et n vaut 2 ou 3, ainsi que leurs sels, solvates et hydrates.

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