Salicylamide derivatives

Details Salicylamide derivatives Salicylamide derivatives

C - Chemistry, Metallurgy

07

C

C07C 237/38 (2006.01) A61K 31/609 (2006.01) A61K 31/625 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) C07C 231/02 (2006.01) C07C 231/12 (2006.01) C07C 237/40 (2006.01) C07D 303/14 (2006.01) C07D 303/22 (2006.01) C07D 303/32 (2006.01) C07D 303/36 (2006.01)

Patent

CA 2393883

Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) and (1b) are useful as anti-inflammatory agents and immunosuppressive agents which exert an effect of inhibiting the activation of NF-.kappa.B with little side effects.

La présente invention concerne des dérivés de salicylamide représentés par les formules (1a) et (1b); des intermédiaires dans la production de ces dérivés; un procédé de production de ces dérivés; et des médicaments contenant ces dérivés comme principe actif. Les dérivés de salicylamide représentés par les formules (1a) et (1b) sont utiles comme agents anti-inflammatoires et comme agents immunosuppresseurs qui exercent un effet inhibant l'activation de NF-.kappa.B avec peu d'effets secondaires.

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