Salmeterol xinafoate with controlled particle size

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 217/10 (2006.01) A61K 31/135 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2165830

The invention relates to particulate products which may be prepared by methods and apparatus using supercritical fluids. More particularly the invention relates to pharmaceutical products, in particular easily handled and easily fluidised crystalline forms of salmeterol xinafoate, with controlled particle size and shape.

L'invention se rapporte à des produits particulaires que l'on peut préparer selon des procédés et avec un appareillage utilisant des fluides supercritiques. L'inventon se rapporte plus spécialement à des produits pharmaceutiques, en particulier à des formes cristallines de xinafoate de salmétérol que l'on peut aisément manipuler et facilement fluidifier, dont la forme et la dimension des particules sont contrôlées.

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