C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01) A61K 39/106 (2006.01) C07K 14/205 (2006.01) C12N 1/36 (2006.01)
Patent
CA 2757224
The present invention relates to Salmonella entehca comprising at least one pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N- glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface. In addition, it is directed to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.
La présente invention concerne une Salmonella enterica comprenant au moins un opéron pgl de Campylobacter jejuni ou l'un de ses dérivés fonctionnels et présentant au moins un N-glycane de Campylobacter jejuni ou l'un de ses dérivés de N-glycane sur sa surface cellulaire. En outre, elle concerne des utilisations médicales et des compositions pharmaceutiques associées ainsi que des procédés de traitement et/ou de prévention d'infections par Campylobacter et éventuellement par Salmonella et des procédés de production de ces souches de Salmonella.
Aebi Markus
Ahuja Umesh
Amber Saba
Ilg Karin
Schwarz Flavio
Eidgenoessische Technische Hochschule Zuerich
Marks & Clerk
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