A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/112 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 1/36 (2006.01)
Patent
CA 2429120
The present invention relates to live attenuated Salmonella strains comprising a first attenuating mutation, that are not capable of making functional RecA. The invention also relates to these bacteria for use in vaccines. Furthermore, the invention relates to vaccines based upon these bacteria, to the use of such bacteria in the manufacture of vaccines and to methods for the preparation of such vaccines.
L'invention concerne des souches vivantes atténuées de Salmonelle, comprenant une première mutation atténuée, ne permettant pas la réalisation d'une protéine RecA fonctionnelle. Cette invention concerne également ces bactéries s'utilisant dans des vaccins, et des vaccins ayant pour base lesdites bactéries. L'invention concerne enfin l'utilisation de telles bactéries dans la fabrication de vaccins et des procédés de préparation de ces vaccins.
Nuijten Petrus Johannes Maria
Witvliet Maarten Hendrik
Akzo Nobel N.v.
Fetherstonhaugh & Co.
Intervet International B.v.
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