Salmonella vaccines

Details Salmonella vaccines Salmonella vaccines

C - Chemistry, Metallurgy

12

N

C12N 1/36 (2006.01) A61K 35/74 (2006.01) A61K 39/112 (2006.01) A61P 31/04 (2006.01) C07K 14/255 (2006.01) C12N 1/21 (2006.01) C12N 15/74 (2006.01) C12Q 1/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2166787

A bacterial cell the virulence of which is attenuated by a first mutation in a PhoP regulon and a second mutation in an aromatic amino acid synthetic gene and bacterial cells the virulence of which is attenuated by a mutation in one or more PhoP-activated genes or one or more PhoP-repressed genes.

Cellule bactérienne dont la virulence est atténuée par une première mutation dans un régulon PhoP, et une seconde mutation dans un gène d'acide aminé aromatique de synthèse, et cellules bactériennes dont la virulence est atténuée par une mutation dans un ou plusieurs gènes activés par PhoP ou un ou plusieurs gènes réprimés par PhoP.

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