Salt form of a dopamine agonist

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/04 (2006.01) A61K 31/5377 (2006.01) A61P 15/00 (2006.01) C07C 309/25 (2006.01)

Patent

CA 2595815

This invention relates to a novel salt form of dopamine agonist 5-[(2R,5S)-5- methyl-4~propylmorpholin-2-yl]pyridin-2-amine (I): More particularly, this invention relates to 5-[(2R,5S)-5-methyl-4-propylmorpholin-2~yl]pyridin-2- amine di-(1 S)-camphorsulfonate (di-S-camsylate) and to processes for the preparation of, intermediates used in the preparation of, compositions containing, and the uses of this salt.

L'invention concerne une nouvelle forme de sel de l'agoniste de la dopamine 5-[(2R,5S)-5-méthyl-4-propylmorpholine-2-yl]pyridine-2-amine (I). Plus précisément, l'invention concerne 5-[(2R,5S)-5-méthyl-4-propylmorpholine-2-yl]pyridine-2-amine di-(1 S)-camphorsulfonate (di-S-camsylate) ainsi que des procédés de préparation de ce sel, des intermédiaires servant dans cette préparation, des compositions contenant ce sel et les utilisations de ce sel.

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