C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/505 (2006.01)
Patent
CA 2469889
The invention relates to succinate and malonate salts of E-2-Methoxy-N-(3-{4- [3- methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)- acetamide having formula (I). More particular the present invention relates to sesquisuccinate and di-malonate salts of formula (I). The invention also relates to pharmaceutical compositions containing the succinate and malonate salts of formula (I). The invention further relates to methods of treating hyperproliferative diseases, such as cancers, in mammals, especially humans by administering the above salts and to methods of preparing the above salts.
L'invention concerne du succinate et du malonate de E-2-méthoxy-N-(3-{4-[3- méthyl-4-(6-méthylpyridin-3-yloxy)-phénylamino]-quinazolin-6-yl}-allyl)-acétamide correspondant à la formule (I). Plus particulièrement, la présente invention concerne le sesquisuccinate et le dimalonate correspondant à la formule (I). L'invention concerne également des compositions pharmaceutiques contenant le succinate et le malonate correspondant à la formule (I). En outre, l'invention concerne des procédés de traitement de maladies hypoprolifératives, telles que les cancers, chez les mammifères, en particulier chez l'homme, lesquels consistent à administrer les sels susmentionnés, ainsi que des procédés de préparation de ces derniers.
Kath John Charles
Richter Daniel Tyler
Pfizer Products Inc.
Smart & Biggar
LandOfFree
Salt forms of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Salt forms of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Salt forms of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1641265