Salt forms of...

Details Salt forms of... Salt forms of...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/505 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2553887

The present invention relates to acid addition salts of 4-[4-methyl-1- piperazinylmethyl]-N-[4-methyl-3-[[4-¢3-pyridinyl-2-pyrimidinyl]amino]phenyl]- benzamide, which are selected from the group consisting of a tartrate salt, such as a (D)(-) tartrate salt or a (L)(+) tartrate salt, a hydrochloride salt, a citrate sat, a malate salt, a fumarate salt, a succinate salt, a benzoate salt, a benzenesulfonate salt, a pamoate salt, a formate salt, a malonate salt, a 1,5-naphthalenedisulfonate salt, a salicylate salt, a cyclohexanesulfamate salt, a lactate salt, a mandelate salt, aq glutarate salt, an adipate salt, a squarate salt, a vanillate salt, an oxaloacetate salt, an ascorbate salt and a sulfate salt.

Cette invention concerne des sels d'addition acides de 4-[4-methyl-1-piperazinylmethyl]-<i>N</i>-[4-methyl-3-[[4-¢3-pyridinyl-2-pyrimidinyl]amino]phenyl]-benzamide, sélectionnés dans le groupe comprenant un sel de tartrate, tel qu'un sel de tartrate (<I>D</I>)(-) ou un sel de tartrate (<I>L</I>)(+), un sel d'hydrochlorure, un sel de citrate, un sel de malate, un sel de fumarate, un sel de succinate, un sel de benzoate, un sel de benzenesulfonate, un sel de pamoate, un sel de formate, un sel de malonate, un sel de 1,5-naphthalènedisulfonate, un salicylate, un sel de cyclohexanesulfamate, un sel de lactate, un sel de mandelate, un sel de glutarate, un sel d'adipate, un sel de squarate, un sel de vanillate, un sel d'oxaloacétate, un sel d'ascorbate et un sel de sulfate.

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