Salt of cd 80 antagonist

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 3/00 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01)

Patent

CA 2643668

The choline salt of the CD80 antagonist compound 4-(6-fluoro-3-oxo-1,3- dihydro-pyrazolo[4,3-c]cinnolin-2-yl)-N-(2,2-difluoro-ethyl)-benzamide (I) has good aqueous solubility and is therefore convenient for pharmaceutical use.

Le sel de choline de l'antagoniste de CD80 4-(6-fluoro-3-oxo-1,3- dihydro-pyrazolo[4,3-c]cinnolin-2-yl)-N-(2,2-difluoro-éthyl)-benzamide (I) présente une bonne solubilité dans l'eau ; son utilisation est donc avantageuse dans le cadre d'applications pharmaceutiques.

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