Salt of furosemide or piretanide as the acid component and...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/09 (2006.01) A61K 31/40 (2006.01) A61K 31/635 (2006.01) C07D 295/155 (2006.01) C07D 307/52 (2006.01) C07D 307/54 (2006.01)

Patent

CA 1161449

ABSTRACT: Salt of furosemide or piretanide as the acid component and penbutolol or (-)-3-[4-[3-(3.4-dimethoxyphenylethyl- amino)-2-hydroxypropoxy]-phenyl]-crotononitrile as the base component. process for its preparation. composition in which it is present and its use The subject of the invention is a salt of furos- emide or piretanide as the acid component and penbutolol or (-)-3-[4-[3-[3.4-dimethoxyphenylethylamino)-2-hydroxy- propoxy]-phenyl]-crotononitrile as the base component, and a process for its preparation, and also a composition containing at least two of the following components: (A) furosemide or piretanide. (B) penbutolol or (-)-3-[4-[3-(3.4-dimethoxy- phenylethylemino)-2-hydroxypropoxy]-phenyl,]-crotononitrile, and (C) the abovementioned salt, and the use of this composition for the treatment of diseases of the coronary and circulatory system.

381058

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