C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/12 (2006.01) A61K 31/4402 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2574660
The salt of oxalic acid with 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)-ethoxy]- benzyl]-thiazolidin-2,4-dione of formula III including its tautomers and solvates. The method of preparation of the salt of oxalic acid with 5-[4-[2-(N- methyl-N-(2-pyridyl)amino)-ethoxy]benzyl]thiazolidin-2,4-dione consists in a reaction of 5-[4-[2-(N-methyl-N-(2-pyridyl)-amino)ethoxy]benzyl]thiazolidin- 2,4-dione of formula I with oxalic acid, the reaction being carried out in a solution in organic solvent or its mixture with water.
La présente invention concerne un sel d'acide oxalique avec 5-[4-[2-(<I>N</I>-méthyl-<I>N</I>-(2-pyridyl)amino)-éthoxy]-benzyl]-thiazolidin-2,4-dione de formule (III) comprenant ses tautomères et ses solvates. Le procédé de préparation du sel d'acide oxalique avec 5-[4-[2-(<I>N</I>-méthyl-<I>N</I>-(2-pyridyl)amino)-éthoxy]-benzyl]-thiazolidin-2,4-dione, comprend une réaction de 5-[4-[2-(<I>N</I>-méthyl-<I>N</I>-(2-pyridyl)-amino)éthoxy]benzyl]thiazolidin-2,4-dione de formule (I) avec de l'acide oxalique, la réaction s'effectuant dans une solution dans du solvant organique ou son mélange avec de l'eau.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Zentiva A.s.
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