Salt solution for colon cleansing

Details Salt solution for colon cleansing Salt solution for colon cleansing

A - Human Necessities

61

K

A61K 33/42 (2006.01) A61K 31/765 (2006.01) A61K 31/77 (2006.01) A61K 33/06 (2006.01)

Patent

CA 2484303

The field of colonic diagnostic and surgical procedures in hampered by the lack of optimal means available to cleanse the colon. A compromise between convenient, distasteful, solid or low volume, hyperosmotic solutions which cause considerable fluid and electrolyte imbalances in patients and large volume, difficult to consume, iso-osmotic solutions has had to be made heretofore. This invention describes a low volume, hyperosmotic solution consisting of sulfate salts with and with out polyethylene glycol. Unlike prior art, this composition is useful for the cleansing of the bowel and, in lower volumes, as a laxative, without producing clinically significant changes in bodily function.

Dans le domaine du diagnostic et des procédures chirurgicales côloniques, le manque de moyens optimaux disponibles pour le nettoyage du côlon constitue un obstacle. Il a fallu trouver un compromis entre des solutions hyperosmotiques, solides ou à volume réduit, pratiques mais désagréables, qui provoquent d'importants déséquilibres fluidiques et électrolytiques chez les patients et des solutions iso-osmotiques, à grand volume, difficiles à consommer. L'invention décrit une solution hyperosmotique à volume réduit constituée de sels de sulfate avec et sans polyéthylèneglycol. Contrairement à ce qui était le cas dans la technique antérieure, cette composition est utile pour le nettoyage des intestins et, à volumes réduits, constitue un laxatif efficace, sans entraîner de changements significatifs du point de vue clinique dans la fonction corporelle.

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