Salt stabilization of antibody-enzyme conjugates heat-dried...

Details Salt stabilization of antibody-enzyme conjugates heat-dried... Salt stabilization of antibody-enzyme conjugates heat-dried...

G - Physics

01

N

G01N 33/535 (2006.01) A61K 39/395 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2048562

Abstract New and useful methods of producing stabilized enzyme antibody conjugates are disclosed which are particularly useful in forming multi-layer immunoassay test devices. In particular, the invention concerns the formation of a manganese ion and enzyme-antibody conjugate in aqueous solution and drying the solution to produce a dry stabilized enzyme-antibody conjugate. Further, this stabilized enzyme-antibody conjugate can be formed on a continuous web and dried in a heat tunnel. This continuous manufacturing process allows for the more efficient production of multi-layer test strips.

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