Salts, addition compounds and complex compounds of...

C - Chemistry – Metallurgy – 07 – C

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C07C 279/24 (2006.01) A23K 1/16 (2006.01) A23L 1/22 (2006.01) A23L 1/30 (2006.01) A61K 8/43 (2006.01) A61K 31/205 (2006.01) A61P 3/02 (2006.01) C07C 229/04 (2006.01)

Patent

CA 2600890

The invention relates to novel salts and/or addition compounds and/or complex compounds of guanidinoacetic acid and malic acid, aspartic acid, ascorbic acid, succinic acid, pyruvic acid, fumaric acid, gluconic acid, .alpha.- oxoglutaric acid, oxalic acid, pyroglutamic acid, 3-nicotinic acid, lactic acid, citric acid, maleic acid, sulphuric acid, acetic acid, formic acid, 2- hydroxybenzoic acid, L-carnitine, acetyl-L-carnitine, taurine, betaine, choline, methionine and lipoic acid, also in the form of potassium-, calcium- or sodium guanidinoacetate. Said salts have improved physiological and therapeutic characteristics and are particularly suitable for use as nutritional supplements, feed and in cosmetic or dermatological preparations, in which their marked stability and excellent bioavailability come to the fore.

L'invention concerne de nouveaux sels et/ou composés d'addition et/ou composés complexes de l'acide guanidinoacétique contenant de l'acide malique, de l'acide aspartique, de l'acide ascorbique, de l'acide succinique, de l'acide pyruvique, de l'acide fumarique, de l'acide gluconique, de l'acide .alpha.-cétoglutarique, de l'acide oxalique, de l'acide pyroglutamique, de l'acide 3-nicotinique, de l'acide lactique, de l'acide citrique, de l'acide maléique, de l'acide sulfurique, de l'acide acétique, de l'acide formique, de l'acide 2-hydroxybenzoïque, de la L-carnitine, de l'acétyl-L-carnitine, de la taurine, de la bétaïne, de la choline, de la méthionine et de l'acide liponique, et en tant que guanidinoacétate de potassium, de calcium ou de sodium. Ces sels présentent de meilleures propriétés physiologiques et thérapeutiques et sont particulièrement adaptés en tant que compléments alimentaires ou nourriture pour animaux, et dans des préparations cosmétiques ou dermatologiques, lesdits sels se caractérisant notamment par leur grande stabilité et leur bonne biodisponibilité.

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