Salts and polymorphs of a potent antidiabetic compound

Details Salts and polymorphs of a potent antidiabetic compound Salts and polymorphs of a potent antidiabetic compound

C - Chemistry, Metallurgy

07

D

C07D 215/20 (2006.01) A61P 3/00 (2006.01) A61P 3/10 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2540536

Salts and polymorphs of a compound useful in the treatment of inflammatory and metabolic conditions and diseases are provided herein. In particular, the invention provides salts and polymorphs of a compound which modulates the expression and/or function of a peroxisome proliferator-activated receptor. The salts and polymorphs are useful for the treatment or prevention of conditions and disorders associated with energy homeostasis such as type II diabetes, lipid metabolism, adipocyte differentiation and inflammation.

L'invention concerne des sels et des polymorphes de composé utile dans le traitement d'affections et de maladies inflammatoires et métaboliques, et en particulier des sels et des polymorphes de composé qui module l'expression et/ou la fonction d'un récepteur activé par proliférateur de peroxisome. Ces produits sont utiles pour le traitement ou la prévention d'affections et de troubles associés à l'homéostase du métabolisme énergétique comme dans le cas du diabète de type II, du métabolisme lipidique, de la différenciation d'adipocyte et de l'inflammation.

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