Salts of 3- (1h-ind0l-3-yl) -4- [2-...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/14 (2006.01) A61K 31/517 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2679484

The invention provides acid addition salts of 3-(1.H.-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, crystalline forms thereof, processes for the preparation thereof, pharmaceutical compositions comprising them and uses thereof in therapeutic treatment.

La présente invention concerne des sels d'addition d'acide de 3-(1.H.-indol-3-yl)-4-[2-(4-méthyl-pipérazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, les formes cristallines de ceux-ci, des procédés pour leur préparation, des compositions pharmaceutiques les comprenant et des utilisations de ceux-ci dans un traitement thérapeutique.

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