C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/517 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2679484
The invention provides acid addition salts of 3-(1.H.-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, crystalline forms thereof, processes for the preparation thereof, pharmaceutical compositions comprising them and uses thereof in therapeutic treatment.
La présente invention concerne des sels d'addition d'acide de 3-(1.H.-indol-3-yl)-4-[2-(4-méthyl-pipérazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, les formes cristallines de ceux-ci, des procédés pour leur préparation, des compositions pharmaceutiques les comprenant et des utilisations de ceux-ci dans un traitement thérapeutique.
Karpinski Piotr
Papoutsakis Dimitris
Yowell Guy
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
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