C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/00 (2006.01) A61K 31/44 (2006.01)
Patent
CA 2587919
The present invention pertains to bis(methanesulfonic acid), bis(ethanesulfonic acid), and camphoric acid salts of chemokine receptor inhibitor N-[2-({(3R)-1-[trans-4-hydroxy-4~(6-methoxypyridin-3-yl)-cyclohexyl]- pyrrolidin-3-yl } amino)-2-oxoethyl]-3~(trifluoromethyl)-benzamide, methods of preparing the same, and methods of using the same.
L'invention concerne des sels d'acide bis(méthanesulfonique), bis(éthanesulfonique) et d'acide camphorique de l'inhibiteur du récepteur chémokine N-[2-({(3R)-1-[trans-4-hydroxy-4-(6-méthoxypyridine-3-yl)-cyclohexyl]-pyrrolidine-3-yl } amino)-2-oxoéthyl]-3-(trifluorométhyl)-benzamide. La présente invention porte également sur des procédés de préparation et d'utilisation de ces sels.
Feng Hao
Glenn Joseph
Li Hui-Yin Harry
Metcalf Brian W.
Xue Chu-Biao
Incyte Corporation
Smart & Biggar
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