Salts of 4-pyrimidinone derivatives, their preparation and...

Details Salts of 4-pyrimidinone derivatives, their preparation and... Salts of 4-pyrimidinone derivatives, their preparation and...

C - Chemistry, Metallurgy

07

D

C07D 403/10 (2006.01) A61K 31/505 (2006.01) C07D 239/36 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2113491

ABSTRACT SALTS OF 4-PYRIMIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Alkanolamine salts and basic amino acid salts of derivatives which may exist in three tautomeric forms of formulae (I), (I'), and (I'') Image Image Image (I) (I') (I'') in which R1 represents a linear or branched (C1-C7)alkyl group, R2 represents either an aryl(C1-C3)alkyl group optionally substituted on the nucleus, or a heteroaryl(C1-C3)alkyl group optionally substituted on the nucleus and, R3 represents either a COOH group, or a 1H-tetrazol- 5-yl group, are useful in therapy as antagonists of angiotensin II.

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