Salts of acetaminophen

Details Salts of acetaminophen Salts of acetaminophen

A - Human Necessities

61

K

A61K 31/165 (2006.01) C07C 231/12 (2006.01) C07C 231/24 (2006.01) C07C 233/25 (2006.01)

Patent

CA 2275174

Isolated salts of acetaminophen are disclosed. Alkali metal and alkaline-earth metal salts of acetaminophen were formed by reacting the free acid of acetaminophen with the corresponding metal hydroxide and then immediately isolating the resulting salt. These salts have been found to be more water soluble and less bitter in taste than the free acid form of acetaminophen.

L'invention concerne des sels isolés d'acétaminophène. On a obtenu des sels métalliques de métal alcalin et alcalino-terreux en faisant réagir l'acide libre d'acétaminophène avec l'hydroxyde métallique correspondant et en isolant immédiatement le sel obtenu. Ces sels se sont avérés être plus solubles dans l'eau et moins amères au goût que la forme d'acide libre d'acétaminophène.

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