Salts of erythromycin a esters

Details Salts of erythromycin a esters Salts of erythromycin a esters

C - Chemistry, Metallurgy

07

H

260/230.3

C07H 17/08 (2006.01)

Patent

CA 1144543

SALTS OF ERYTHROMYCIN A ESTERS Abstract of the Disclosure Highly water-soluble erythromycin A derivatives wherein the desosamine moiety is quaternized with an acyloxy-, benzoyloxy- or alkoxycarbonyl-(or carboxy)-acyl- methyl iodide, bromine or chloride and esterified in the 2- position with loweralkyl or -(CH2)nCO2R", wherein R" is H, loweralkyl or substituted loweralkyl and n is an integer from 1-5. These new esters readily convert to erythromycin A upon administration to warm-blooded animals.

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