Salts of imidazole-5-carboxylic acid derivatives, a method...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/10 (2006.01) A61K 31/41 (2006.01) A61K 31/4164 (2006.01) A61P 9/12 (2006.01) C07D 233/68 (2006.01) C07D 233/90 (2006.01) C07D 405/10 (2006.01)

Patent

CA 2671816

The present application discloses the pharmaceutically acceptable salts of imidazol-5-carboxylic acid derivatives, preparation methods and medicament compositions thereof. The present salts have good solubility in conventional solvents, such as methanol or water, and have good bioavailability in vivo. These salts can be used as therapeutical agents against hypertension.

Sels pharmaceutiquement acceptables de dérivés d'acide imidazol-5-carboxylique, procédés de préparation et compositions médicamenteuses correspondantes. Ces sels ont une bonne solubilité dans les solvants classiques, du type méthanol ou eau, et ils ont une bonne biodisponibilité in vivo. On peut les utiliser comme agents thérapeutiques contre l'hypertension.

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