Salts of peptides with carboxy-terminated polyesters

Details Salts of peptides with carboxy-terminated polyesters Salts of peptides with carboxy-terminated polyesters

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 9/16 (2006.01) A61K 38/00 (2006.01) A61K 38/09 (2006.01) A61K 47/34 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2136751

This invention relates to novel salts composed of a cation derived from a peptide containing at least one basic group and an anion derived from a carboxy-terminated polyester, processes for the manufacture of such salts, and the use of such salts in the manufacture of extended release pharmaceutical compositions. The salts of the invention possess a variety of properties which are useful in the formulation of extended release pharmaceutical compositions, whether the salts are in pure form or are in admixture with either an excess of the peptide in its free, unbound form or an excess of the free polyester.

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