C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01)
Patent
CA 2689663
The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
La présente invention concerne des formes de sel de (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile qui se révèlent utiles pour la modulation de l'activité Janus kinase et se révèlent utiles pour le traitement de maladies liées à l'activité des Janus kinases, notamment des maladies liées à l'immunité, des troubles cutanés, des troubles myéloïdes proliférants, le cancer et d'autres maladies.
Li Hui-Yin
Rodgers James D.
Incyte Corporation
Smart & Biggar
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