Sample detection to initiate timing of an electrochemical assay

Details Sample detection to initiate timing of an electrochemical assay Sample detection to initiate timing of an electrochemical assay

G - Physics

01

N

G01N 27/416 (2006.01) G01N 27/42 (2006.01) G01N 27/49 (2006.01) G01N 33/48 (2006.01) G01N 33/487 (2006.01)

Patent

CA 2311431

An electrochemical assay includes a method for determining with great accuracy the time at which an applied sample bridges a gap between the electrodes of an electrochemical cell. The method involves applying a constant small current across the gap, while monitoring the potential difference between the electrodes. The time at which the sample bridges the gap is marked by a sharp drop in the potential. A constant voltage is applied after the sample is detected, and the current and/or charge through the sample is monitored over a period of time. From the measured current or charge, the analyte concentration of interest can be calculated.

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