Sample diluent for measurement with ion-selective electrodes...

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G01N 27/26 (2006.01) G01N 27/333 (2006.01) G01N 27/416 (2006.01) G01N 33/487 (2006.01) G01N 33/50 (2006.01) G01N 33/84 (2006.01)

Patent

CA 2048142

A body fluid sample is diluted with a diluent which comprises an aqueous solution containing bis(2- hydroxyethyl)-iminotris(hydroxymethyl)methane and boric acid to obtain a diluted body fluid sample, and the ion concentration in the diluted body fluid sample is determined with ion-selective electrodes, whereby the variation width of pH in the diluted body fluid sample can be held down to a narrow range; resultingly, the determination can be made without exerting adverse effects on the ion-selective electrodes and errors in determination can be markedly reduced as compared with cases where the conventional diluents are used.

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