Sample evaporative control

Details Sample evaporative control Sample evaporative control

B - Operations, Transporting

01

L

B01L 3/00 (2006.01) B01J 19/16 (2006.01) G01N 1/34 (2006.01) G01N 35/00 (2006.01)

Patent

CA 2337007

Devices and methods are provided using microfluidic devices for manipulating small volumes and determining a variety of chemical and physical events. The devices rely upon an opening to the atmosphere of a small volume in a zone, where a sample is placed in the zone where evaporation can occur. The zone is maintained in contact with a liquid medium that serves to replenish the liquid in the zone and maintain the composition of the mixture in the zone substantially constant. The diffusion of components in the zone is restricted during the course of the determination by the liquid flux into the zone.

L'invention concerne des dispositifs et procédés d'utilisation de dispositifs microfluidiques destinés à la manipulation de petits volumes et à la détermination d'événements chimiques et physiques. Les dispositifs s'appuient sur une ouverture dans l'atmosphère d'un petit volume dans une zone, un échantillon étant placé dans la zone où une évaporation peut se produire. La zone est maintenue en contact avec un milieu liquide, ce qui permet de reconstituer le liquide dans la zone et de maintenir sensiblement constante la composition du mélange dans la zone. La diffusion des composants dans la zone est limitée, pendant la détermination, par le flux de liquide dans la zone.

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