Sampling and analysis of reactions by trapping reaction...

C - Chemistry – Metallurgy – 40 – B

Patent

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Details

C40B 20/08 (2006.01) B01L 3/00 (2006.01) C40B 30/00 (2006.01) C40B 60/10 (2006.01) C40B 60/12 (2006.01) G01N 21/77 (2006.01) G01N 30/90 (2006.01) G01N 31/22 (2006.01) G01N 21/31 (2006.01) G01N 21/78 (2006.01)

Patent

CA 2307617

Methods and devices for rapidly analyzing groups of reactions aredisclosed. The method includes the steps of contacting a fluid sample from one of the reaction mixtures with a sorbent, trapping at least one component of the fluid sample on the sorbent, and detecting the at least one component of the fluid sample trapped on the sorbent. The contacting step, the trapping step, and the detecting step are carried out at least once for each of the reaction mixtures in rapid serial or parallel fashion. The present invention is useful for screening combinatorial libraries, especially libraries of catalysts made through parallel synthesis, but the disclosed methods and devices can be used to analyze a broad spectrum of chemical transformations.

La présente invention concerne des procédés et des dispositifs permettant l'analyse rapide de groupes de réactions. Ce procédé consiste à mettre en contact un échantillon fluide provenant d'un des mélanges de réaction avec un sorbant, à piéger au moins un composant de l'échantillon fluide sur le sorbant, et à détecter le composant ainsi piégé sur le sorbant. Les étapes de mise en contact, de piégeage et de détection sont effectuées au moins une fois pour chacun des mélanges de réaction, en mode série ou parallèle rapide. Par ailleurs, cette invention est utilisée pour le criblage de librairies combinatoires, particulièrement les librairies de catalyseurs conçues par synthèse parallèle, ces procédés et dispositifs pouvant être utilisés pour analyser un large spectre de transformations chimiques.

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