Sapogenin derivatives, their synthesis and use, and methods...

Details Sapogenin derivatives, their synthesis and use, and methods... Sapogenin derivatives, their synthesis and use, and methods...

A - Human Necessities

61

K

A61K 31/585 (2006.01) A61P 9/02 (2006.01) A61P 9/04 (2006.01) A61P 11/06 (2006.01) A61P 21/00 (2006.01) A61P 21/04 (2006.01) A61P 25/08 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 27/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 2442150

The invention discloses certain steroidal sapogenins and derivatives thereof, and their use in the treatment of cognitive dysfunction, non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, and receptor loss in the absence of cognitive, neural and neuromuscular impairment. Methods of synthesis, treatment and pharmaceutical compositions are also disclosed.

L'invention se rapporte à des sapogénines stéroïdiques et à leurs dérivés, ainsi qu'à leur utilisation dans le traitement des dysfonctionnements cognitifs, des neurodégénérescences non cognitives, des dégénérescences neuromusculaires non cognitives, et de la perte de récepteurs en l'absence de déficiences cognitives, neuronales et neuromusculaires. L'invention concerne également des procédés de synthèse, des traitements et des compositions pharmaceutiques.

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