Scaffold material

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/00 (2006.01) C12M 3/00 (2006.01) D04H 1/72 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2645541

The object is to provide a scaffold material which has excellent mechanical strength and an excellent capability of growing a cell and is suitable as a cell culture substrate or a prosthesis. Disclosed is a scaffold material for growing a cell. The scaffold material comprises an aggregate of fibers, has a three-dimensional structure composed of two bottom faces and side faces, and satisfies the following requirements (1) to (4): (1) the fibers are oriented in the side-wise direction; (2) each of the fibers has a diameter of 0.05 to 50 µm; (3) each of the fibers is composed mainly of a biocompatible polymer; and (4) the scaffold material has an apparent density of 95 to 350 kg/m3.

La présente invention vise à proposer un matériau pour matrice ayant une excellente résistance mécanique et une excellente aptitude à la croissance cellulaire et adapté en tant que substrat pour une culture cellulaire ou une prothèse. L'invention concerne un matériau pour matrice destiné à la croissance cellulaire. Ledit matériau comprend un agrégat de fibres, a une structure tridimensionnelle composée de deux faces inférieures et faces latérales et répond aux exigences (1) à (4) suivantes : (1) les fibres sont orientées dans le sens latéral ; (2) chacune des fibres a un diamètre de 0,05 à 50 µm ; (3) chacune des fibres est composée principalement d'un polymère biocompatible ; et (4) ledit matériau a une densité apparente de 95 à 350 kg/m3.

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