Scaled-up production of liposome-encapsulated hemoglobin

Details Scaled-up production of liposome-encapsulated hemoglobin Scaled-up production of liposome-encapsulated hemoglobin

A - Human Necessities

61

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167/114

A61K 9/127 (2006.01) A61K 38/42 (2006.01) B01J 13/02 (2006.01)

Patent

CA 1289072

ABSTRACT OF THE DISCLOSURE A method for making sterile liposome-encapuslated hemoglobin having an oxygen carrying capacity of 20 vol/%, a half-life of 15-20 hours as measured in mice, with the liposome made from chloroform, HSPC, cholesterol, negatively charged DMPG and alpha-tocopherol.

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