Scanning of biochemical microassays by kelvin microprobe

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) G01Q 60/30 (2010.01) G01N 33/53 (2006.01) G01Q 10/02 (2010.01)

Patent

CA 2309412

There is provided a process of detecting nucleic acid duplex formation on a substrate having nucleic acid immobilized thereon, which comprises subjecting such a substrate suspected of containing nucleic acid duplex formation to a scanning Kelvin microprobe, and analyzing the contact potential difference determined by the scanning Kelvin microprobe to detect nucleic acid duplex formation.

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