Schizophrenia associated gene, proteins and biallelic markers

Details Schizophrenia associated gene, proteins and biallelic markers Schizophrenia associated gene, proteins and biallelic markers

Category

C - Chemistry, Metallurgy

Subcategory

12

Subsubcategory

N

IPC codes

C12N 15/85 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G06F 17/30 (2006.01) G06F 17/50 (2006.01)

Type

Patent

Patent number

CA 2388205

Description

The invention concerns the human g35030 gene, polynucleotides, polypeptides biallelic markers, and human chromosome 13q31-q33 biallelic markers. The invention also concerns the association established between schizophrenia and bipolar disorder and the biallelic markers and the g35030 gene and nucleotide sequences. The invention provides means to identify compounds useful in the treatment of schizophrenia, bipolar disorder and related diseases, means to determine the predisposition of individuals to said disease as well as means for the disease diagnosis and prognosis.

L'invention porte sur les marqueurs bialléliques des gènes humains, des polynucléotides et des polypeptides g35030, et les marqueurs bialléliques du chromosome humain 13q31-q33. L'invention porte également sur l'association établie entre la schizophrénie et les troubles bipolaires d'une part, et les marqueurs bialléliques et les gènes et les séquences g35030 d'autre part. L'invention porte en outre sur des moyens d'identification de composés utiles pour le traitement de la schizophrénie, de troubles bipolaires et de maladies associées, sur des moyens permettant de déterminer la prédisposition d'individus à ces maladies, ainsi que sur des moyens permettant de diagnostiquer ou de pronostiquer lesdites maladies.

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