Schizophrenia related gene and protein

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2418779

The invention relates to polynucleotides of the PAPAP gene, polypeptides encoded by the PAPAP gene, and antibodies directed specifically against such polypeptides. The invention also concerns methods for the treatment or diagnosis of schizophrenia, bipolar disorder or related CNS disorder. The invention also concerns the interaction of PAPAP with schizophrenia candidate gene g34872.

L'invention porte sur des polynucléotides du gène PAPAP, sur des polypeptides codées par le gène PAPAP et sur de anticorps dirigés de manière spécifique contre ces polypeptides. L'invention porte également sur des procédés de traitement ou de diagnostic de la schizophrénie, d'une maladie affective bipolaire ou de troubles connexes du système nerveux central. L'invention porte encore sur l'interaction du gène PAPAP avec le gène candidat g34872 de la schizophrénie.

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