Scintillator composition for a radioassay, and method for...

G - Physics – 01 – N

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G01N 23/00 (2006.01) G01N 21/76 (2006.01)

Patent

CA 2531125

A medium for a scintillation assay includes a fluorescent Coumarin dye, typically having a Stokes shift of at least 50 nm and a fluorescence in the range of 460-500 nm. The composition may further include secondary scintillator materials which as PPO, DPA, bis-MSB, BiBuQ, and the like. The scintillator medium may be a liquid medium or a solid medium. Also disclosed is an assay utilizing the material of the present invention, as well as a specifically solid~ state scintillator medium incorporating Coumarin 153 and BiBuQ.

Selon l'invention, un milieu destiné à un dosage par scintillation comprend un colorant coumarinique fluorescent présentant habituellement un décalage de Stokes d'au moins 50 nm et une fluorescence comprise entre 460 et 500 nm. Cette composition peut en outre comprendre des matières scintillantes secondaires, telles que PPO, DPA, bis-MSB, BiBuQ et analogues. Le milieu scintillant peut être un milieu liquide ou un milieu solide. L'invention concerne également un dosage faisant appel à la matière de la présente invention, ainsi qu'un milieu scintillant spécifiquement à l'état solide comprenant de la coumarine 153 et du BiBuQ.

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