Scorpionate-like pendant macrocyclic ligands, complexes and...

C - Chemistry – Metallurgy – 07 – D

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C07D 255/02 (2006.01) A61K 31/395 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2487908

Substituted 1,4,7-triazacyclononane-N,N',N"-triacetic acid compounds with a pendant donor amino group, metal complexes thereof, compositions thereof, and methods of use in diagnostic imaging and treatment of a cellular disorder.

L'invention a trait à des composés substitués de 1,4,7-triazacyclononane-<I>N,N',N''</I>-acide triacétique, qui possèdent un groupement aminé donneur pendant, à des complexes métalliques de ces derniers, à des compositions les contenant, et à des procédés d'utilisation dans l'imagerie diagnostique et pour le traitement d'un trouble cellulaire.

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