Screening assay methods and systems using target pooling

B - Operations – Transporting – 44 – C

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B44C 1/22 (2006.01) C07K 14/705 (2006.01) C12M 3/00 (2006.01) C12Q 1/37 (2006.01) C12Q 1/48 (2006.01) G01N 1/30 (2006.01) G01N 15/14 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01) G01N 33/558 (2006.01) B01L 3/00 (2006.01)

Patent

CA 2407064

Methods, devices and systems for increasing the throughput of screening assays by pooling multiple target systems, which allow a library of different materials, e.g., test compounds, to be screened against the pooled targets to determine whether any of the materials affect one or more of the target systems. In preferred aspects, functioning of individual target systems is identified by differences in physical, chemical and/or optical properties particular to the target system in a target pool.

La présente invention concerne des techniques, des dispositifs et des systèmes permettant d'augmenter la production des analyses de criblage par regroupement de multiples systèmes cible, ce qui permet de cribler une bibliothèque de différents matériaux, par exemple des composés test, contre les cibles regroupées de façon à déterminer si un de ces matériaux influence un ou plusieurs des systèmes cible. Dans des aspects préférés, on identifie le fonctionnement de systèmes cible individuels par des différences de propriétés physiques, chimiques et/ou optiques propres au système cible dans un regroupement cible.

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