C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 31/7105 (2006.01) A61K 39/40 (2006.01) A61P 31/00 (2006.01) C07K 14/31 (2006.01) C12N 15/11 (2006.01) C12N 15/74 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2576643
Isolation of an iron regulated, nme-gene operon (designated sbn) from Staphylococcus aureus (RN6390), responsible for the biosynthesis of staphylobactm, a novel S. aureus siderophore Methods for treating or preventing a disease or condition caused by S. aureus infection, as well as methods for identifying agents that inhibit the biosynthesis of staphylobactm or inhibit the expression of genes in said sbn operon are further disclosed.
L'invention concerne le rôle que joue l'opéron de Staphylococcus aureus (S. aureus) sbn dans la biosynthèse d'un nouveau sidérophore. La présente invention porte également sur des procédés pour cribler des composés qui inhibent la biosynthèse de ce sidérophore.
Dale Suzanne
Heinrichs David E.
Gowling Lafleur Henderson Llp
The University Of Western Ontario
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