Screening compounds for the ability to alter the production...

Details Screening compounds for the ability to alter the production... Screening compounds for the ability to alter the production...

G - Physics

01

N

G01N 33/53 (2006.01) C12Q 1/00 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01) G01N 33/60 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2258348

This invention provides methods of screening compounds for their ability to alter the production of A.beta. (x41) alone or in combination with A.beta. (x40). The methods involve administering compounds to cells, specifically measuring the amounts of A.beta. (x40) and A.beta. (x41) produced by the cells, and comparing these amounts to that produced by the cells without administration of the compounds.

La présente invention concerne des procédés de criblage de composés capables de modifier la production de A.beta. (x?41) seul ou combiné avec A.beta. (x?40). Ces procédés consistent à administrer des composés à des cellules, à mesurer les quantités spécifiques de A.beta. (x?40) et de A.beta. (x?41) produites par lesdites cellules et à comparer ces quantités avec les quantités produites par des cellules auxquelles les composés n'ont pas été administrés.

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