Screening for anti-ovulatory compounds

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2491642

Screening methods for identifying compounds that are useful as contraceptives are provided. In particular, the compounds inhibit the interaction between steroidogenic factor 1 (SF-1) and nuclear receptor interacting protein (Nrip1) or the up-regulate SF-1 expression.

L'invention concerne des procédés de criblage visant à identifier des composés utiles comme contraceptifs. Ces composés inhibent en particulier l'interaction entre le facteur stéroïdogène 1 (SF-1) et la protéine interagissant avec le récepteur nucléaire (Nrip1), ou régulent positivement l'expression de SF-1.

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